Hpx Antibody, HRP conjugated

Code CSB-PA010723LB01RA
Size US$166
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Product Details

Full Product Name
Rabbit anti-Rattus norvegicus (Rat) Hpx Polyclonal antibody
Uniprot No.
Target Names
Hpx
Alternative Names
Hpx antibody; Hemopexin antibody
Raised in
Rabbit
Species Reactivity
Rat
Immunogen
Recombinant Rat Hemopexin protein (24-460AA)
Immunogen Species
Rattus norvegicus (Rat)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
Gene References into Functions
  1. Data suggest that apo-hemopexin isolated from plasma exchibits low endogenous levels of tyrosine nitration in the peptide YYCFQGNQFLR in the heme-binding site of human hemopexin, which was similarly nitrated in rabbit and rat hemopexins; heme binding by hemopexin declined as tyrosine nitration proceeded in vitro. PMID: 28596380
  2. Hemopexin was identified as upregulated protein in the small intestine exposed to indomethacin. PMID: 22486875
  3. hemopexin mRNA was low or undetectable in livers of hypophysectomized rats, however, daily treatment with bovine growth hormone for 10 days restored hemopexin mRNA levels PMID: 12850285
  4. intracellular calcium and protein kinase C activation are involved in the regulation of Hpx. PMID: 12850286
Subcellular Location
Secreted.
Protein Families
Hemopexin family
Tissue Specificity
Expressed by the liver and secreted in plasma.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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